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Administration of Antibody to the Lung Protects Mice against Pneumonic Plague

Intratracheal delivery of aerosolized monoclonal antibodies with specificity for Yersinia pestis LcrV and F1 antigens protected mice in a model of pneumonic plague. These data support the utility of inhaled antibodies as a fast-acting postexposure treatment for plague.

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Bibliographische Detailangaben
Hauptverfasser: Hill, Jim, Eyles, Jim E., Elvin, Stephen J., Healey, Gareth D., Lukaszewski, Roman A., Titball, Richard W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459704/
https://ncbi.nlm.nih.gov/pubmed/16622253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.5.3068-3070.2006
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