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Endoplasmic Reticulum-Associated Degradation Is Required for Cold Adaptation and Regulation of Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae

Endoplasmic reticulum-associated degradation (ERAD) mediates the turnover of short-lived and misfolded proteins in the ER membrane or lumen. In spite of its important role, only subtle growth phenotypes have been associated with defects in ERAD. We have discovered that the ERAD proteins Ubc7 (Qri8),...

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Autors principals: Loertscher, Jennifer, Larson, Lynnelle L., Matson, Clinton K., Parrish, Mark L., Felthauser, Alicia, Sturm, Aaron, Tachibana, Christine, Bard, Martin, Wright, Robin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459677/
https://ncbi.nlm.nih.gov/pubmed/16607018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.5.4.712-722.2006
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