Endoplasmic Reticulum-Associated Degradation Is Required for Cold Adaptation and Regulation of Sterol Biosynthesis in the Yeast Saccharomyces cerevisiae

Endoplasmic reticulum-associated degradation (ERAD) mediates the turnover of short-lived and misfolded proteins in the ER membrane or lumen. In spite of its important role, only subtle growth phenotypes have been associated with defects in ERAD. We have discovered that the ERAD proteins Ubc7 (Qri8),...

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Main Authors: Loertscher, Jennifer, Larson, Lynnelle L., Matson, Clinton K., Parrish, Mark L., Felthauser, Alicia, Sturm, Aaron, Tachibana, Christine, Bard, Martin, Wright, Robin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459677/
https://ncbi.nlm.nih.gov/pubmed/16607018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.5.4.712-722.2006
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