In Silico Pharmacogenetics: Warfarin Metabolism

A recently developed murine haplotype-based computational method was used to identify genetic factors regulating the metabolism of warfarin, a commonly prescribed anticoagulant with a narrow therapeutic index and a large variation in individual dosing. The amount of warfarin and 9 identified metabol...

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Autors principals: Guo, Yingying, Weller, Paul, Farrell, Erin, Cheung, Paul, Fitch, Bill, Clark, Douglas, Wu, Shao-yong, Wang, Jianmei, Liao, Guochun, Zhang, Zhaomei, Allard, John, Cheng, Janet, Nguyen, Anh, Jiang, Sharon, Shafer, Steve, Usuka, Jonathan, Masjedizadeh, Mohammad, Peltz, Gary
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459533/
https://ncbi.nlm.nih.gov/pubmed/16680137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1195
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