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Explanation of the Stability of Thermophilic Proteins Based on Unique Micromorphology

Two mesophilic/thermophilic variants of the G-domain of the elongation factor Tu were studied via molecular dynamics simulations. By analyzing the simulation data via the Voronoi space tessellation, we have found that the two proteins have the same macromolecular packing, while the water-exposed sur...

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Detalles Bibliográficos
Main Authors: Melchionna, Simone, Sinibaldi, Raffaele, Briganti, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459513/
https://ncbi.nlm.nih.gov/pubmed/16533850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078972
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