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Explanation of the Stability of Thermophilic Proteins Based on Unique Micromorphology

Two mesophilic/thermophilic variants of the G-domain of the elongation factor Tu were studied via molecular dynamics simulations. By analyzing the simulation data via the Voronoi space tessellation, we have found that the two proteins have the same macromolecular packing, while the water-exposed sur...

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Hlavní autoři: Melchionna, Simone, Sinibaldi, Raffaele, Briganti, Giuseppe
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459513/
https://ncbi.nlm.nih.gov/pubmed/16533850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078972
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