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Explanation of the Stability of Thermophilic Proteins Based on Unique Micromorphology

Two mesophilic/thermophilic variants of the G-domain of the elongation factor Tu were studied via molecular dynamics simulations. By analyzing the simulation data via the Voronoi space tessellation, we have found that the two proteins have the same macromolecular packing, while the water-exposed sur...

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Detalhes bibliográficos
Main Authors: Melchionna, Simone, Sinibaldi, Raffaele, Briganti, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459513/
https://ncbi.nlm.nih.gov/pubmed/16533850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078972
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