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Prion Disease: Exponential Growth Requires Membrane Binding

A hallmark feature of prions, whether in mammals or yeast and fungi, is exponential growth associated with fission or autocatalysis of protein aggregates. We have employed a rigorous kinetic analysis to recent data from transgenic mice lacking a glycosylphosphatidylinositol membrane anchor to the no...

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Bibliografski detalji
Glavni autori: Cox, Daniel L., Sing, Rajiv R. P., Yang, Sichun
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459498/
https://ncbi.nlm.nih.gov/pubmed/16581847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.081703
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