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Suppression of prion protein in livestock by RNA interference

Given the difficulty of applying gene knockout technology to species other than mice, we decided to explore the utility of RNA interference (RNAi) in silencing the expression of genes in livestock. Short hairpin RNAs (shRNAs) were designed and screened for their ability to suppress the expression of...

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Bibliografiske detaljer
Main Authors: Golding, Michael C., Long, Charles R., Carmell, Michelle A., Hannon, Gregory J., Westhusin, Mark E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1459347/
https://ncbi.nlm.nih.gov/pubmed/16567624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600813103
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