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Membrane-associated heparan sulfate is not required for rAAV-2 infection of human respiratory epithelia
BACKGROUND: Adeno-associated virus type 2 (AAV-2) attachment and internalization is thought to be mediated by host cell membrane-associated heparan sulfate proteoglycans (HSPG). Lack of HSPG on the apical membrane of respiratory epithelial cells has been identified as a reason for inefficient rAAV-2...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
BioMed Central
2006
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1459113/ https://ncbi.nlm.nih.gov/pubmed/16630361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-3-29 |
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