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Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease

Genetic variation in neuregulin 1 (NRG1) is associated with schizophrenia. The disease-associated SNPs are noncoding, and their functional implications remain unknown. We hypothesized that differential expression of the NRG1 gene explains its association to the disease. We examined four of the disea...

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Bibliografske podrobnosti
Main Authors: Law, Amanda J., Lipska, Barbara K., Weickert, Cynthia Shannon, Hyde, Thomas M., Straub, Richard E., Hashimoto, Ryota, Harrison, Paul J., Kleinman, Joel E., Weinberger, Daniel R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458952/
https://ncbi.nlm.nih.gov/pubmed/16618933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602002103
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