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Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage

Centromeres are the chromosomal loci that facilitate segregation, and, in most eukaryotes, they encompass extensive regions of genomic DNA. Topoisomerase-II has been identified as a crucial regulator of segregation in a wide range of organisms and exhibits premitotic accumulation at centromeres. Con...

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Detalhes bibliográficos
Main Authors: Kelly, John M., McRobert, Louisa, Baker, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458945/
https://ncbi.nlm.nih.gov/pubmed/16617116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510363103
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