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Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage
Centromeres are the chromosomal loci that facilitate segregation, and, in most eukaryotes, they encompass extensive regions of genomic DNA. Topoisomerase-II has been identified as a crucial regulator of segregation in a wide range of organisms and exhibits premitotic accumulation at centromeres. Con...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458945/ https://ncbi.nlm.nih.gov/pubmed/16617116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510363103 |
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