Lack of IL-15 results in the suboptimal priming of CD4(+) T cell response against an intracellular parasite

IFN-γ-producing CD4(+) T cells, although important for protection against acute Toxoplasma gondii infection, can cause gut pathology, which may prove to be detrimental for host survival. Here we show that mice lacking IL-15 gene develop a down-regulated IFN-γ-producing CD4(+) T cell response against...

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Detalles Bibliográficos
Main Authors: Combe, Crescent L., Moretto, Magali M., Schwartzman, Joseph D., Gigley, Jason P., Bzik, David J., Khan, Imtiaz A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458934/
https://ncbi.nlm.nih.gov/pubmed/16614074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506180103
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