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Lack of IL-15 results in the suboptimal priming of CD4(+) T cell response against an intracellular parasite
IFN-γ-producing CD4(+) T cells, although important for protection against acute Toxoplasma gondii infection, can cause gut pathology, which may prove to be detrimental for host survival. Here we show that mice lacking IL-15 gene develop a down-regulated IFN-γ-producing CD4(+) T cell response against...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458934/ https://ncbi.nlm.nih.gov/pubmed/16614074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506180103 |
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