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Spatiotemporal control of spindle midzone formation by PRC1 in human cells
We have examined the role of PRC1, a midzone-associated, microtubule bundling, Cdk substrate protein, in regulating the spatiotemporal formation of the midzone in HeLa cells. Cdk-mediated phosphorylation of PRC1 in early mitosis holds PRC1 in an inactive monomeric state. During the metaphase-to-anap...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458854/ https://ncbi.nlm.nih.gov/pubmed/16603632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506926103 |
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