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A structural role for ATP in the formation and stability of the human origin recognition complex

The locally restricted recruitment of the multisubunit origin recognition complex (ORC) to eukaryotic chromosomes defines the position of origins of DNA replication. In budding yeast and metazoans the DNA binding activity of ORC is stimulated by ATP and requires an AAA+-type nucleotide binding domai...

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Detalhes bibliográficos
Main Authors: Ranjan, Anand, Gossen, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458761/
https://ncbi.nlm.nih.gov/pubmed/16549788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510305103
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