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A structural role for ATP in the formation and stability of the human origin recognition complex
The locally restricted recruitment of the multisubunit origin recognition complex (ORC) to eukaryotic chromosomes defines the position of origins of DNA replication. In budding yeast and metazoans the DNA binding activity of ORC is stimulated by ATP and requires an AAA+-type nucleotide binding domai...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1458761/ https://ncbi.nlm.nih.gov/pubmed/16549788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510305103 |
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