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A structural role for ATP in the formation and stability of the human origin recognition complex

The locally restricted recruitment of the multisubunit origin recognition complex (ORC) to eukaryotic chromosomes defines the position of origins of DNA replication. In budding yeast and metazoans the DNA binding activity of ORC is stimulated by ATP and requires an AAA+-type nucleotide binding domai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ranjan, Anand, Gossen, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458761/
https://ncbi.nlm.nih.gov/pubmed/16549788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510305103
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