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A structural role for ATP in the formation and stability of the human origin recognition complex

The locally restricted recruitment of the multisubunit origin recognition complex (ORC) to eukaryotic chromosomes defines the position of origins of DNA replication. In budding yeast and metazoans the DNA binding activity of ORC is stimulated by ATP and requires an AAA+-type nucleotide binding domai...

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Autori principali: Ranjan, Anand, Gossen, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458761/
https://ncbi.nlm.nih.gov/pubmed/16549788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510305103
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