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Structural insight into the assembly and conformational activation of human origin recognition complex
The function of the origin recognition complex (ORC) in DNA replication is highly conserved in recognizing and marking the initiation sites. The detailed molecular mechanisms by which human ORC is reconfigured into a state competent for origin association remain largely unknown. Here, we present str...
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| Publicado no: | Cell Discov |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7684300/ https://ncbi.nlm.nih.gov/pubmed/33298899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-00232-3 |
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