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Progression of prostate cancer by synergy of AKT with genotropic and nongenotropic actions of the androgen receptor

Classic work by Huggins and Hodges demonstrated that human prostate cancer regresses dramatically during antihormonal therapy but recurs frequently with androgen independence. Perturbations in the androgen receptor (AR) and PTEN–AKT signaling axes are significantly correlated with the progression of...

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Detalles Bibliográficos
Main Authors: Xin, Li, Teitell, Michael A., Lawson, Devon A., Kwon, Andrew, Mellinghoff, Ingo K., Witte, Owen N.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458510/
https://ncbi.nlm.nih.gov/pubmed/16682621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602567103
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