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An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate.

Minor groove binding compounds related to distamycin A bind DNA with high sequence selectivity, recognizing sites which contain various combinations of A.T and G.C base pairs. These molecules have the potential to deliver cross-linking agents to the minor groove of a target DNA sequence. We have stu...

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Udgivet i:Nucleic Acids Res
Principais autores: Fagan, P A, Spielmann, H P, Sigurdsson, S, Rink, S M, Hopkins, P B, Wemmer, D E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8628693/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.8.1566
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