Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naïve CD4(+) T cells

The mechanisms controlling induction of anergy at the level of naïve CD4(+) T cells are poorly understood but thought to reflect limited contact with costimulatory molecules during T cell antigen receptor (TCR) ligation. To clarify this question, naïve TCR transgenic CD4(+) cells were exposed to spe...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ragazzo, Jennifer L., Ozaki, Minette E., Karlsson, Lars, Peterson, Per A., Webb, Susan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120881/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011397798
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