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Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naïve CD4(+) T cells

The mechanisms controlling induction of anergy at the level of naïve CD4(+) T cells are poorly understood but thought to reflect limited contact with costimulatory molecules during T cell antigen receptor (TCR) ligation. To clarify this question, naïve TCR transgenic CD4(+) cells were exposed to spe...

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Detalhes bibliográficos
Main Authors: Ragazzo, Jennifer L., Ozaki, Minette E., Karlsson, Lars, Peterson, Per A., Webb, Susan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14575/
https://ncbi.nlm.nih.gov/pubmed/11120881
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