The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal arms.
The HMG box of human LEF-1 (hLEF-1, formerly TCF1alpha) has been expressed in four forms: a parent box of 81 amino acids and constructs having either a 10 amino acid C-terminal extension, a 9 amino acid N-terminal extension, or both. These four species have been compared for DNA binding and bending...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
1996
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1047 |
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