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The DNA bend angle and binding affinity of an HMG box increased by the presence of short terminal arms.

The HMG box of human LEF-1 (hLEF-1, formerly TCF1alpha) has been expressed in four forms: a parent box of 81 amino acids and constructs having either a 10 amino acid C-terminal extension, a 9 amino acid N-terminal extension, or both. These four species have been compared for DNA binding and bending...

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Publicat a:Nucleic Acids Res
Autors principals: Lnenicek-Allen, M, Read, C M, Crane-Robinson, C
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1047
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