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SRE elements are binding sites for the fusion protein EWS-FLI-1.

EWS-FLI-1 is a chimeric protein produced in most Ewing's sarcomas. It results from the fusion of the N-terminal-encoding region of the EWS gene to the C-terminal DNA-binding domain (the ETS domain) encoded by the FLI-1 ets family gene. Both EWS-FLI-1 and FLI-1 proteins function as transcription fact...

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Publicat a:Nucleic Acids Res
Autors principals: Magnaghi-Jaulin, L, Masutani, H, Robin, P, Lipinski, M, Harel-Bellan, A
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145748/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604338/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1052
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