SRE elements are binding sites for the fusion protein EWS-FLI-1.
EWS-FLI-1 is a chimeric protein produced in most Ewing's sarcomas. It results from the fusion of the N-terminal-encoding region of the EWS gene to the C-terminal DNA-binding domain (the ETS domain) encoded by the FLI-1 ets family gene. Both EWS-FLI-1 and FLI-1 proteins function as transcription fact...
I tiakina i:
| I whakaputaina i: | Nucleic Acids Res |
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| Ngā kaituhi matua: | , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Oxford University Press
1996
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1052 |
| Ngā Tūtohu: |
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