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Interaction of tRNA (uracil-5-)-methyltransferase with NO2Ura-tRNA.

tRNA in which uracil is completely replaced by 5-nitro-uracil was prepared by substituting 5-nitro-UTP for UTP in an in vitro transcription reaction. The rationale was that the 5-nitro substituent activates the 6-carbon of the Ura heterocycle towards nucleophiles, and hence could provide mechanism-b...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Gu, X, Matsuda, A, Ivanetich, K M, Santi, D V
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604339/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1059
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