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Quinazoline-2,4(1H,3H)-dione as a substitute for thymine in triple-helix forming oligonucleotides: a reassessment.

A major limitation in triple-helix formation arises from the weak energy of interaction between the third strand and the double-stranded target. We tried to increase the stacking interaction contribution within the third strand by extending the aromatic domain of thymine. We report here the use of 2...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Michel, J, Toulmé, J J, Vercauteren, J, Moreau, S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC145745/
https://ncbi.nlm.nih.gov/pubmed/8604348
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