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The capacity of microsomally-activated cyclophosphamide to induce immunosuppression in vitro.

Cyclophosphamide (CY) was activated in vitro with washed rat liver microsomes and cofactors. Pretreatment of mouse spleen cells in vitro with the activated drug abolished their capacity to give a primary antibody response to SRBC and levan on transfer to irradiated syngeneic recipients. However, res...

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Bibliografische gegevens
Hoofdauteur: Shand, F L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1978
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457449/
https://ncbi.nlm.nih.gov/pubmed/33118
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