Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation.
The p53 tumour suppressor protein is a potent transcription factor which plays a central role in the defence of cells against DNA damage and the propagation of malignant clones. We have previously shown that phosphorylation of serine 386 in mouse p53 by the growth- associated protein kinase, casein...
שמור ב:
| הוצא לאור ב: | Nucleic Acids Res |
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| Principais autores: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
1996
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8604347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.6.1119 |
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