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Molecular cloning and functional analysis of a human cDNA encoding an Escherichia coli AlkB homolog, a protein involved in DNA alkylation damage repair.

The Escherichia coli AlkB protein is involved in protecting cells against mutation and cell death induced specifically by SN2-type alkylating agents such as methyl methanesulfonate (MMS). A human cDNA encoding a polypeptide homologous to E.coli AlkB was discovered by searching a database of expresse...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Wei, Y F, Carter, K C, Wang, R P, Shell, B K
Format: Artigo
Language:Inglês
Published: Oxford University Press 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8600462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.5.931
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