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Angiotensin II and Stretch activate NADPH oxidase to Destabilize Cardiac Kv4.3 Channel mRNA
Pathological and physiological hypertrophy of the heart is associated with decreased expression of the Kv4.3 transient outward current (Ito) channel. The downregulation of channel mRNA and protein, which may be proarrhythmic, is recapitulated with cultured neonatal rat ventricular myocytes treated w...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1457039/ https://ncbi.nlm.nih.gov/pubmed/16556864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000218989.52072.e7 |
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