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X Chromosomes Alternate between Two States prior to Random X-Inactivation

Early in the development of female mammals, one of the two X chromosomes is silenced in half of cells and the other X chromosome is silenced in the remaining half. The basis of this apparent randomness is not understood. We show that before X-inactivation, the two X chromosomes appear to exist in di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mlynarczyk-Evans, Susanna, Royce-Tolland, Morgan, Alexander, Mary Kate, Andersen, Angela A, Kalantry, Sundeep, Gribnau, Joost, Panning, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1457015/
https://ncbi.nlm.nih.gov/pubmed/16669701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040159
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