Expression of S100A8 correlates with inflammatory lung disease in congenic mice deficient of the cystic fibrosis transmembrane conductance regulator

BACKGROUND: Lung disease in cystic fibrosis (CF) patients is dominated by chronic inflammation with an early and inappropriate influx of neutrophils causing airway destruction. Congenic C57BL/6 CF mice develop lung inflammatory disease similar to that of patients. In contrast, lungs of congenic BALB...

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Hauptverfasser: Tirkos, Sam, Newbigging, Susan, Nguyen, Van, Keet, Mary, Ackerley, Cameron, Kent, Geraldine, Rozmahel, Richard F
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2006
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456967/
https://ncbi.nlm.nih.gov/pubmed/16571124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-51
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