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GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover

G protein-coupled receptor kinase interactors (GITs) regulate focal adhesion (FA) turnover, cell spreading, and motility through direct interaction with paxillin and the Rac-exchange factor Pak-interacting exchange factor β (βPIX). However, it is not clear whether GITs function to activate or repres...

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Bibliografiske detaljer
Main Authors: Frank, Scott R, Adelstein, Molly R, Hansen, Steen H
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456948/
https://ncbi.nlm.nih.gov/pubmed/16628223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601092
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