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Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

The poly(A)-binding protein (PABP) is a unique translation initiation factor in that it binds to the mRNA 3′ poly(A) tail and stimulates recruitment of the ribosome to the mRNA at the 5′ end. PABP activity is tightly controlled by the PABP-interacting protein 2 (Paip2), which inhibits translation by...

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Bibliographische Detailangaben
Hauptverfasser: Yoshida, Madoka, Yoshida, Kaori, Kozlov, Guennadi, Lim, Nadia S, De Crescenzo, Gregory, Pang, Zhiyu, Berlanga, Juan Jose, Kahvejian, Avak, Gehring, Kalle, Wing, Simon S, Sonenberg, Nahum
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456944/
https://ncbi.nlm.nih.gov/pubmed/16601676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601079
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