Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

The poly(A)-binding protein (PABP) is a unique translation initiation factor in that it binds to the mRNA 3′ poly(A) tail and stimulates recruitment of the ribosome to the mRNA at the 5′ end. PABP activity is tightly controlled by the PABP-interacting protein 2 (Paip2), which inhibits translation by...

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Autores principales: Yoshida, Madoka, Yoshida, Kaori, Kozlov, Guennadi, Lim, Nadia S, De Crescenzo, Gregory, Pang, Zhiyu, Berlanga, Juan Jose, Kahvejian, Avak, Gehring, Kalle, Wing, Simon S, Sonenberg, Nahum
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456944/
https://ncbi.nlm.nih.gov/pubmed/16601676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601079
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