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Type A and B RNase P RNAs are interchangeable in vivo despite substantial biophysical differences

We show that structural type A and B bacterial ribonuclease P (RNase P) RNAs can fully replace each other in vivo despite the many reported differences in their biogenesis, biochemical/biophysical properties and enzyme function in vitro. Our findings suggest that many of the reported idiosyncrasies...

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Detalhes bibliográficos
Main Authors: Wegscheid, Barbara, Condon, Ciarán, Hartmann, Roland K
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456918/
https://ncbi.nlm.nih.gov/pubmed/16470227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400641
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