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Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration

Human mitochondrial respiration is distinct from that of most plants, microorganisms and even some metazoans in that it reduces molecular oxygen only through the highly cyanide-sensitive enzyme cytochrome c oxidase. Here we show that expression of the cyanide-insensitive alternative oxidase (AOX), r...

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Autori principali: Hakkaart, Gerrit A J, Dassa, Emmanuel P, Jacobs, Howard T, Rustin, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456879/
https://ncbi.nlm.nih.gov/pubmed/16322757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400601
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