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Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration

Human mitochondrial respiration is distinct from that of most plants, microorganisms and even some metazoans in that it reduces molecular oxygen only through the highly cyanide-sensitive enzyme cytochrome c oxidase. Here we show that expression of the cyanide-insensitive alternative oxidase (AOX), r...

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Autors principals: Hakkaart, Gerrit A J, Dassa, Emmanuel P, Jacobs, Howard T, Rustin, Pierre
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456879/
https://ncbi.nlm.nih.gov/pubmed/16322757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400601
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