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The Extent of Linkage Disequilibrium Caused by Selection on G6PD in Humans
The gene coding for glucose-6-phosphate dehydrogenase (G6PD) is subject to positive selection by malaria in some human populations. The G6PD A− allele, which is common in sub-Saharan Africa, is associated with deficient enzyme activity and protection from severe malaria. To delimit the impact of sel...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456824/ https://ncbi.nlm.nih.gov/pubmed/16020776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.048140 |
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