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The Extent of Linkage Disequilibrium Caused by Selection on G6PD in Humans

The gene coding for glucose-6-phosphate dehydrogenase (G6PD) is subject to positive selection by malaria in some human populations. The G6PD A− allele, which is common in sub-Saharan Africa, is associated with deficient enzyme activity and protection from severe malaria. To delimit the impact of sel...

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Bibliografski detalji
Glavni autori: Saunders, Matthew A., Slatkin, Montgomery, Garner, Chad, Hammer, Michael F., Nachman, Michael W.
Format: Artigo
Jezik:Inglês
Izdano: Copyright © 2005 by the Genetics Society of America 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456824/
https://ncbi.nlm.nih.gov/pubmed/16020776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.048140
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