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Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia.

Pro-inflammatory cytokines, such as tumour necrosis factor (TNF) and free radicals, such as nitric oxide (NO), are mediators of endotoxaemia. Catecholamines are in clinical use to treat the haemodynamic consequences of severe septic shock. Beta-adrenergic agonists exert many of their effects by elev...

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Bibliografiske detaljer
Main Authors: Szabó, C, Haskó, G, Zingarelli, B, Németh, Z H, Salzman, A L, Kvetan, V, Pastores, S M, Vizi, E S
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456713/
https://ncbi.nlm.nih.gov/pubmed/9038718
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