Crystallization of a complex between the Fab fragment of a human immunoglobulin M (IgM) rheumatoid factor (RF-AN) and the Fc fragment of human IgG4.

Rheumatoid factors (RF) are the characteristic autoantibodies found in patients with rheumatoid arthritis. They recognize epitopes in the Fc region of immunoglobulin G (IgG) and are often of the IgM isotype. In order to analyse the nature of RF-Fc interactions, we have crystallized a complex between...

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Main Authors: Sohi, M K, Corper, A L, Wan, T, Steinitz, M, Jefferis, R, Beale, D, He, M, Feinstein, A, Sutton, B J, Taussig, M J
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456622/
https://ncbi.nlm.nih.gov/pubmed/8881769
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