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Viral transactivators specifically target distinct cellular protein kinases that phosphorylate the RNA polymerase II C-terminal domain.

Phosphorylation of the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II has been implicated as an important step in transcriptional regulation. Previously, we reported that a cellular CTD kinase, TAK, is targeted by the human immunodeficiency virus transactivator Tat. In th...

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Udgivet i:Nucleic Acids Res
Principais autores: Herrmann, C H, Gold, M O, Rice, A P
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC145661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8602364/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/24.3.501
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