Viral transactivators specifically target distinct cellular protein kinases that phosphorylate the RNA polymerase II C-terminal domain.

Ítems similars

• The HIV transactivator TAT binds to the CDK-activating kinase and activates the phosphorylation of the carboxy-terminal domain of RNA polymerase II
  per: Cujec, Thomas P., et al.
  Publicat: (1997)
• Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor.
  per: Herrmann, C H, et al.
  Publicat: (1995)
• The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA Binding
  per: Cowling, Victoria H., et al.
  Publicat: (2007)
• Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain by the Bur1 Cyclin-Dependent Kinase
  per: Murray, Stuart, et al.
  Publicat: (2001)
• Cross-talk Among RNA Polymerase II Kinases Modulates C-terminal Domain Phosphorylation
  per: Devaiah, Ballachanda N., et al.
  Publicat: (2012)