Down-regulation of cyclooxygenase-2 (COX-2) by interleukin-1 receptor antagonist in human monocytes.

Cyclooxygenase (COX) is the key rate-limiting enzyme in the synthesis of prostanoids from arachidonic acid. Two isoforms of COX have been described in mammalian cells, referred to as cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). COX-1 is a constitutively expressed enzyme; COX-2 is an induci...

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Bibliografiske detaljer
Main Authors: Porreca, E, Reale, M, Di Febbo, C, Di Gioacchino, M, Barbacane, R C, Castellani, M L, Baccante, G, Conti, P, Cuccurullo, F
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456547/
https://ncbi.nlm.nih.gov/pubmed/8958057
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