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Neurospora Strains Harboring Mitochondrial Disease-Associated Mutations in Iron-Sulfur Subunits of Complex I
We subjected the genes encoding the 19.3-, 21.3c-, and 51-kDa iron-sulfur subunits of respiratory chain complex I from Neurospora crassa to site-directed mutagenesis to mimic mutations in human complex I subunits associated with mitochondrial diseases. The V135M substitution was introduced into the...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Copyright © 2005 by the Genetics Society of America
2005
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456533/ https://ncbi.nlm.nih.gov/pubmed/15956670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.041517 |
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