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Chimaeric monoclonal antibodies encoded by the human VH26 gene from naïve transgenic mice display a wide range of antigen-binding specificities.

To elucidate the molecular basis for the ability of antibodies encoded by the human VH26 heavy-chain variable region gene to react with diverse antigens, we have generated 34 hybridomas secreting chimaeric monoclonal antibodies (human mu heavy chain/mouse light chains) from transgenic mice. The tran...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Harmer, I J, Mageed, R A, Kaminski, A, Charles, P, Brüggemann, M, Mackworth-Young, C G
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456425/
https://ncbi.nlm.nih.gov/pubmed/8690448
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