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A multiple-site-specific heteroduplex tracking assay as a tool for the study of viral population dynamics

Rapidly evolving entities, such as viruses, can undergo complex genetic changes in the face of strong selective pressure. We have developed a modified heteroduplex tracking assay (HTA) capable of detecting the presence of single, specific mutations or sets of linked mutations. The initial applicatio...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Resch, Wolfgang, Parkin, Neil, Stuelke, Erin L., Watkins, Terri, Swanstrom, Ronald
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120887/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011511298
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