A multiple-site-specific heteroduplex tracking assay as a tool for the study of viral population dynamics

Rapidly evolving entities, such as viruses, can undergo complex genetic changes in the face of strong selective pressure. We have developed a modified heteroduplex tracking assay (HTA) capable of detecting the presence of single, specific mutations or sets of linked mutations. The initial applicatio...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Resch, Wolfgang, Parkin, Neil, Stuelke, Erin L., Watkins, Terri, Swanstrom, Ronald
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.011511298
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