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Role of leukotriene B4 in the interleukin-4-induced human mononuclear phagocyte activation.

Interleukin-4 (IL-4) induced a time- and dose-dependent production of leukotriene B4 (LTB4) by human resting monocytes indicating that IL-4 induced the activation of the 5-lipoxygenase pathway in resting human monocytes. Maximal effect was observed in the presence of 10 ng/ml IL-4, and in kinetics e...

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Detalhes bibliográficos
Main Authors: Dugas, N, Dugas, B, Kolb, J P, Yamaoka, K, Delfraiss, J F, Damais, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456343/
https://ncbi.nlm.nih.gov/pubmed/8774354
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